Can science define morality?

We've all heard the argument that "you can't get an ought from an is" (or most of us with any history of discussing ethics have).
However I was linked to a couple of long youtube videos (over an hour each, I won't post them yet because I want to initiate a discussion here and get people's views not bore you all with long videos). The basic premise of one of the people in the videos was that science can define morality, and there could in theory be scientific tests devised to tell if an act is moral or immoral (a caveat, in practice it would be very complicated to have those tests in reality, because of the hugely complex nature of reality and the interactions of actions and consequences).
Their very basic argument is this: Morality is dependent on minds existing. In a universe full of inanimate matter there is no such thing as a moral or immoral act, just rocks bashing together. Morality is about well-being, the more well-being is caused or promoted by an action the more moral it is. We can imagine a world where the worst possible situation exists for everything. The least possible well-being. We can also imagine a world where the best possible situation exists. Both of those situations are measurable by science, certain conditions exist in reality independent of any thinking thing. It's no real stretch from there to posit that the situations in between could also be measured for how much well-being exists. By comparing, if we could, the well-being caused by decision A as opposed to decision B we could scientifically state that decision B is more moral.
The most obvious objection is that well-being is a very loose and fluffy term and we probably can't agree on what well-being comprises. The response to that is that we cannot readily define good health, yet that doesn't stop us having a science of medicine. There's stuff to do with not throwing up all the time, and not being in constant pain, but any definition of good health also has fuzzy edges.
Do you agree? Can we get to morality through scientific methods and reasoning alone or should science stay mute on this topic?
(a note - this thread isn't for bashing one moral judgement or another, or to bash religion, or for any other kind of bashing, or for promoting either of those things either. The topic at hand is whether morality is in theory testable, measurable and definable by science)
However I was linked to a couple of long youtube videos (over an hour each, I won't post them yet because I want to initiate a discussion here and get people's views not bore you all with long videos). The basic premise of one of the people in the videos was that science can define morality, and there could in theory be scientific tests devised to tell if an act is moral or immoral (a caveat, in practice it would be very complicated to have those tests in reality, because of the hugely complex nature of reality and the interactions of actions and consequences).
Their very basic argument is this: Morality is dependent on minds existing. In a universe full of inanimate matter there is no such thing as a moral or immoral act, just rocks bashing together. Morality is about well-being, the more well-being is caused or promoted by an action the more moral it is. We can imagine a world where the worst possible situation exists for everything. The least possible well-being. We can also imagine a world where the best possible situation exists. Both of those situations are measurable by science, certain conditions exist in reality independent of any thinking thing. It's no real stretch from there to posit that the situations in between could also be measured for how much well-being exists. By comparing, if we could, the well-being caused by decision A as opposed to decision B we could scientifically state that decision B is more moral.
The most obvious objection is that well-being is a very loose and fluffy term and we probably can't agree on what well-being comprises. The response to that is that we cannot readily define good health, yet that doesn't stop us having a science of medicine. There's stuff to do with not throwing up all the time, and not being in constant pain, but any definition of good health also has fuzzy edges.
Do you agree? Can we get to morality through scientific methods and reasoning alone or should science stay mute on this topic?
(a note - this thread isn't for bashing one moral judgement or another, or to bash religion, or for any other kind of bashing, or for promoting either of those things either. The topic at hand is whether morality is in theory testable, measurable and definable by science)